No persistent effect of intravenous immunoglobulins in patients with narcolepsy with cataplexy

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Narcolepsy with cataplexy in monozygotic twins

INTRODUCTION This paper describes narcolepsy with cataplexy in two monozygotic twin sisters. OBJECTIVE To clinically illustrate the involvement of neurological, genetic and immunologic systems in narcolepsy. MATERIAL AND METHODS We performed a restropective study of these patients that were followed in the sleep medicine ambulatory clinic of the Faculdade de Medicina de Ribeirao Preto. RE...

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Cortical morphometry in narcolepsy with cataplexy.

The sleep-wake disorder narcolepsy with cataplexy is associated with the loss of hypocretin-(orexin-) producing neurons in the lateral hypothalamus. Several studies have reported abnormal cerebral activation in patients with narcolepsy with cataplexy. It remains unclear, however, whether these functional changes are related to structural alterations, particularly at the cortical level. To quant...

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ژورنال

عنوان ژورنال: Journal of Neurology

سال: 2008

ISSN: 0340-5354,1432-1459

DOI: 10.1007/s00415-008-0996-2